Recombinant Osteopontin Improves Neurological Functional Recovery and Protects Against Apoptosis via PI3K/Akt/GSK-3β Pathway Following Intracerebral Hemorrhage

机译：重组骨桥蛋白通过脑出血后PI3K / Akt /GSK-3β途径改善神经功能恢复并防止凋亡

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

BackgroundThis study aimed to investigate the potential neuroprotective effect of recombinant osteopontin (r-OPN) on apoptotic changes via modulating phosphoinositide-3-kinase/Akt/glycogen synthase kinase 3 beta (PI3K/Akt/GSK-3β) signaling in a rat model of intracerebral hemorrhage (ICH).

机译：背景本研究旨在研究重组骨桥蛋白（r-OPN）通过调节磷酸肌醇-3-激酶/ Akt /糖原合酶激酶3 beta（PI3K / Akt /GSK-3β）信号转导对凋亡变化的潜在神经保护作用。脑出血（ICH）。

著录项

期刊名称 Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
作者
Wenqian Zhang; Ying Cui; Junling Gao; Ran Li; Xiaohua Jiang; Yanxia Tian; Kaijie Wang; Jianzhong Cui;
展开▼
作者单位

展开▼
年(卷),期 1923(24),
年度 1923
页码 1588–1596
总页数 9
原文格式 PDF
正文语种
中图分类
关键词
Apoptosis, Cerebral Hemorrhage, Osteopontin, Phosphatidylinositol 3-Kinases;

机译：凋亡;脑出血;骨桥蛋白;磷脂酰肌醇3-激酶;

相似文献

外文文献
中文文献
专利

1. The extract of Gnaphalium affine D. Don protects against H2O2-induced apoptosis by targeting PI3K/AKT/GSK-3 beta signaling pathway in cardiomyocytes [J] . Meng Xiang-wen, He Can-xia, Chen Xiao, Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2021,第1期

机译：脑脊液D. DIN的提取物通过在心肌细胞中靶向PI3K / AKT / GSK-3β信号传导途径来保护H2O2诱导的细胞凋亡
2. Phosphorylated GSK-3 beta protects stress-induced apoptosis of myoblasts via the PI3K/Akt signaling pathway [J] . Molecular medicine reports . 2020,第1期

机译：磷酸化的GSK-3β通过PI3K / AKT信号通路保护肌细胞的应激诱导的凋亡
3. Activation of the Melanocortin-1 Receptor by NDP-MSH Attenuates Oxidative Stress and Neuronal Apoptosis through PI3K/Akt/Nrf2 Pathway after Intracerebral Hemorrhage in Mice [J] . Siming Fu, Xu Luo, Xuan Wu, Oxidative Medicine and Cellular Longevity . 2020,第47期

机译：通过NDP-MSH激活Melanocortin-1受体通过小鼠脑出血后通过PI3K / AKT / NRF2途径衰减氧化应激和神经元细胞凋亡
4. Determining the functional role of keratin filaments in apoptosis via the PI3K/Akt signaling pathway using LTQ Orbitrap MS/MS analysis [C] . Nancy Fernandes, Nicole Morin Jaskiewicz, David H. Townson, ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：使用LTQ orbitrap MS / MS分析确定通过PI3K / AKT信号通路凋亡中角蛋白长丝在细胞凋亡中的功能作用
5. The multi-targeted receptor tyrosine kinase inhibitor, linifanib (ABT-869), induces apoptosis and inhibits proliferation of leukemia cells through phosphoinositide-3 kinase (PI3K)/AKT-dependent signaling pathways. [D] . Hernandez, Jenny Elizabeth. 2010

机译：多靶点受体酪氨酸激酶抑制剂利尼法尼（ABT-869）通过磷酸肌醇3激酶（PI3K）/ AKT依赖性信号传导途径诱导凋亡并抑制白血病细胞的增殖。
6. TREM2 activation attenuates neuroinflammation and neuronal apoptosis via PI3K/Akt pathway after intracerebral hemorrhage in mice [O] . Shengpan Chen, Jianhua Peng, Prativa Sherchan, 2020

机译：小鼠脑出血后TREM2激活通过PI3K / Akt途径减轻神经炎症和神经元凋亡
7. Activation of the Melanocortin-1 Receptor by NDP-MSH Attenuates Oxidative Stress and Neuronal Apoptosis through PI3K/Akt/Nrf2 Pathway after Intracerebral Hemorrhage in Mice [O] . Siming Fu, Xu Luo, Xuan Wu, 2020

机译：通过NDP-MSH激活Melanocortin-1受体通过小鼠脑出血后通过PI3K / AKT / NRF2途径衰减氧化应激和神经元细胞凋亡

Recombinant Osteopontin Improves Neurological Functional Recovery and Protects Against Apoptosis via PI3K/Akt/GSK-3β Pathway Following Intracerebral Hemorrhage

摘要

著录项

相似文献

相关主题

期刊订阅