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Two-dimensional FSI simulation of closing dynamics of a tilting disc mechanical heart valve

机译:倾斜盘式机械心脏瓣膜关闭动力学的二维FSI模拟

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摘要

The fluid dynamics during valve closure resulting in high shear flows and large residence times of particles has been implicated in platelet activation and thrombus formation in mechanical heart valves. Our previous studies with bi-leaflet valves have shown that large shear stresses induced in the gap between the leaflet edge and the valve housing results in relatively high platelet activation levels whereas flow between the leaflets results in shed vortices not conducive to platelet damage. In this study we compare the result of closing dynamics of a tilting disc valve with that of a bi-leaflet valve. The two-dimensional fluid-structure interaction analysis of a tilting disc valve closure mechanics is performed with a fixed grid Cartesian mesh flow solver with local mesh refinement, and a Lagrangian particle dynamic analysis for computation of potential for platelet activation. Throughout the simulation the flow remains in the laminar regime and the flow through the gap width is marked by the development of a shear layer which separates from the leaflet downstream of the valve. Zones of re-circulation are observed in the gap between the leaflet edge and the valve housing on the major orifice region of the tilting disc valve and are seen to be migrating towards the minor orifice region. Jet flow is observed at the minor orifice region and a vortex is formed which sheds in the direction of fluid motion as observed in experiments using PIV measurements. The activation parameter computed for the tilting disc valve, at the time of closure was found to be 2.7 times greater than that of the bi-leaflet mechanical valve and was found to be in the vicinity of the minor orifice region mainly due to the migration of vortical structures from the major to the minor orifice region during the leaflet rebound of the closing phase.
机译:瓣膜关闭过程中的流体动力学导致高剪切流量和较大的颗粒停留时间,这与机械心脏瓣膜的血小板活化和血栓形成有关。我们以前对双叶瓣的研究表明,在小叶边缘和瓣膜壳体之间的间隙中引起的大剪切应力导致相对较高的血小板活化水平,而小叶之间的流动导致脱落的涡流,不利于血小板的破坏。在这项研究中,我们比较了可倾式碟形阀和双叶式瓣膜的关闭动力学结果。使用具有局部网格细化的固定网格笛卡尔网格流量解算器和用于计算血小板活化潜力的拉格朗日粒子动力学分析,来进行可倾盘阀关闭力学的二维流体-结构相互作用分析。在整个模拟过程中,流动保持层流状态,通过间隙宽度的流动以剪切层的形成为标志,该剪切层与瓣膜下游的小叶分开。在瓣膜瓣膜主孔区域的小叶边缘和瓣膜壳体之间的间隙中观察到了再循环区域,并且看到这些区域正朝着小孔区域迁移。如在使用PIV测量的实验中所观察到的,在小孔区域观察到了射流,并形成了沿流体运动方向脱落的涡流。发现在关闭时为可倾盘阀计算的激活参数是双叶机械阀的激活参数的2.7倍,并且发现在小孔口区域附近,主要是由于在闭合阶段的瓣叶回弹期间,从主要孔口区域到次要孔口区域的旋涡结构。

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