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IgG4-Associated Cholangitis Can Mimic Hilar Cholangiocarcinoma

机译:IgG4相关胆管炎可模拟肝门胆管癌

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摘要

IgG4-associated cholangitis can mimic hilar cholangiocarcinoma. Previously reported patients with IgG4-associated cholangitis mimicking cholangiocarcinoma had elevated serum IgG4 levels and long-segment biliary strictures. However, in the absence of other diagnostic criteria for malignancy, IgG4-associated cholangitis should remain a consideration among patients with normal serum IgG4 and a hilar mass suspicious for cholangiocarcinoma. The presence of a hilar mass and a malignant-appearing biliary stricture in two patients with normal serum IgG4 prompted further evaluation and subsequent concomitant liver and bile duct resection and reconstruction. The diagnosis of IgG4-associated cholangitis was established during the pathologic evaluation of the resected specimens. IgG4-associated cholangitis is a known imitator of hilar cholangiocarcinoma and should be considered in the differential diagnosis even among serologically IgG4-negative patients with a hilar mass prior to operative resection.
机译:IgG4相关性胆管炎可模仿肺门胆管癌。先前报道的模仿胆管癌的IgG4相关性胆管炎患者血清IgG4水平升高且长段胆道狭窄。但是,在缺乏其他恶性诊断标准的情况下,血清IgG4正常且可疑胆管癌的肺门肿块的患者仍应考虑IgG4相关性胆管炎。在两名血清IgG4正常的患者中,肝门肿块和恶性胆道狭窄的存在促使进一步评估,并随后进行肝胆管切除和重建。 IgG4相关性胆管炎的诊断是在切除标本的病理评估过程中确定的。 IgG4相关性胆管炎是已知的肝门胆管癌的模仿者,即使在手术切除前有肝门肿块的血清学IgG4阴性的患者中,也应考虑在鉴别诊断中予以考虑。

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