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Scientific iconoclasm and active imagination: synthetic cells as techno-scientific mandalas

机译:科学的圣像破坏和活跃的想象力:合成细胞作为技术科学的曼荼罗

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摘要

Metaphors allow us to come to terms with abstract and complex information, by comparing it to something which is structured, familiar and concrete. Although modern science is “iconoclastic”, as Gaston Bachelard phrases it (i.e. bent on replacing living entities by symbolic data: e.g. biochemical and mathematical symbols and codes), scientists are at the same time prolific producers of metaphoric images themselves. Synthetic biology is an outstanding example of a technoscientific discourse replete with metaphors, including textual metaphors such as the “Morse code” of life, the “barcode” of life and the “book” of life. This paper focuses on a different type of metaphor, however, namely on the archetypal metaphor of the mandala as a symbol of restored unity and wholeness. Notably, mandala images emerge in textual materials (papers, posters, PowerPoints, etc.) related to one of the new “frontiers” of contemporary technoscience, namely the building of a synthetic cell: a laboratory artefact that functions like a cell and is even able to replicate itself. The mandala symbol suggests that, after living systems have been successfully reduced to the elementary building blocks and barcodes of life, the time has now come to put these fragments together again. We can only claim to understand life, synthetic cell experts argue, if we are able to technically reproduce a fully functioning cell. This holistic turn towards the cell as a meaningful whole (a total work of techno-art) also requires convergence at the “subject pole”: the building of a synthetic cell as a practice of the self, representing a turn towards integration, of multiple perspectives and various forms of expertise.
机译:通过将隐喻与结构化,熟悉和具体的事物进行比较,隐喻可以使我们对抽象和复杂的信息有所了解。尽管现代科学是“破坏性的”,正如加斯顿·巴切拉德(Gaston Bachelard)所说的那样(即倾向于用符号数据代替生物实体:例如生化和数学符号和代码),但科学家同时还是隐喻图像本身的丰富生产者。合成生物学是一个充满了隐喻的技术科学话语的杰出例子,包括文本隐喻,例如生活的“摩尔斯电码”,生活的“条形码”和生活的“书”。本文着重于另一种类型的隐喻,即曼陀罗的原型隐喻,作为恢复统一和整体性的象征。值得注意的是,曼陀罗图像出现在与当代技术新的“前沿”之一有关的文本材料(纸张,海报,PowerPoint等)中,即合成细胞的构建:一种实验室人工制品,其功能类似于细胞,甚至是能够自我复制。曼陀罗符号表明,在将生命系统成功地简化为生命的基本组成部分和条形码之后,现在该将这些碎片重新组合在一起的时候了。合成细胞专家认为,如果我们能够从技术上复制功能完备的细胞,那么我们只能声称了解生命。这种将细胞作为有意义的整体(技术领域的整体工作)的整体转向还需要在“主题极点”融合:将合成细胞构建为自我的一种实践,代表着向多个方向的整合。观点和各种形式的专业知识。

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