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Risk Factors for Macro- and Microvascular Complications among Older Adults with Diagnosed Type 2 Diabetes: Findings from The Irish Longitudinal Study on Ageing

机译:被诊断为2型糖尿病的成年人中大血管和微血管并发症的危险因素:爱尔兰关于衰老的纵向研究的发现

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摘要

Objective. To explore risk factors for macro- and microvascular complications in a nationally representative sample of adults aged 50 years and over with type 2 diabetes in Ireland. Methods. Data from the first wave of The Irish Longitudinal Study on Ageing (TILDA) (2009–2011) was used in cross-sectional analysis. The presence of doctor diagnosis of diabetes, risk factors, and macro- and microvascular complications were determined by self-report. Gender-specific differences in risk factor prevalence were assessed with the chi-squared test. Binomial regression analysis was conducted to explore independent associations between established risk factors and diabetes-related complications. Results. Among 8175 respondents, 655 were classified as having type 2 diabetes. Older age, being male, a history of smoking, a lower level of physical activity, and a diagnosis of high cholesterol were independent predictors of macrovascular complications. Diabetes diagnosis of 10 or more years, a history of smoking, and a diagnosis of hypertension were associated with an increased risk of microvascular complications. Older age, third-level education, and a high level of physical activity were protective factors (p < 0.05). Conclusions. Early intervention to target modifiable risk factors is urgently needed to reduce diabetes-related morbidity in the older population in Ireland.
机译:目的。在爱尔兰具有全国代表性的50岁以上2型糖尿病成年人中,探讨大血管和微血管并发症的危险因素。方法。爱尔兰纵向老龄化研究(TILDA)(2009-2011)的第一波数据用于横截面分析。通过自我报告确定医生诊断为糖尿病,危险因素以及大血管和微血管并发症。用卡方检验评估危险因素患病率的性别特异性差异。进行了二项式回归分析,以探讨已确定的危险因素与糖尿病相关并发症之间的独立关联。结果。在8175位受访者中,有655位被归为2型糖尿病。年龄较大,男性,吸烟史,体力活动水平较低以及胆固醇含量高是大血管并发症的独立预测因子。糖尿病诊断为10年或10年以上,吸烟史和高血压诊断与微血管并发症风险增加相关。年龄较大,受过第三级教育和较高水平的体育锻炼是保护因素(p <0.05)。结论。迫切需要针对可改变的危险因素进行早期干预,以减少爱尔兰老年人口与糖尿病相关的发病率。

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