Safety and convenience of once-weekly somapacitan in adult GH deficiency: a 26-week randomized controlled trial

机译：成人每周GH缺乏的每周一次Somapacitan的安全性和便利性：一项为期26周的随机对照试验

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摘要

ObjectiveSomapacitan is a reversible albumin-binding growth hormone (GH) derivative, developed for once-weekly administration. This study aimed to evaluate the safety of once-weekly somapacitan vs once-daily Norditropin^®. Local tolerability and treatment satisfaction were also assessed.

机译：ObjectiveSomapacitan是一种可逆的白蛋白结合生长激素（GH）衍生物，开发用于每周一次的给药。这项研究旨在评估每周一次索马培他坦与每日一次诺地罗汀^{®的安全性。还评估了局部耐受性和治疗满意度。}

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期刊名称 European Society of Endocrinology Open Access
作者
Gudmundur Johannsson; Ulla Feldt-Rasmussen; Ida Holme Håkonsson; Henrik Biering; Patrice Rodien; Shigeyuki Tahara; Andrew Toogood; Michael Højby Rasmussen; Henrik Biering; Wolfram Karges; Alexander Mann; Jens Sandahl Christiansen; Troels Krarup Hansen; Marianne Andersen; Ulla Feldt-Rasmussen; Sine Borresen; Patrice Rodien; Françoise Borson-Chazot; Véronique Kerlan; Bertrand Cariou; Bruno Verges; Shigeyuki Tahara; Akira Matsuno; Koji Takano; Tetsuya Tagami; Yutaka Takahashi; Toshikazu Takahashi; Masahiro Yamamoto; Gudmundur Johannsson; Charlotte Höybye; Eva-Marie Erfurth; William Drake; Claire Higham; Robert Murray; Andrew Toogood; Antonia Brooke;
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年(卷),期 -1(178),5
年度 -1
页码 491–499
总页数 9
原文格式 PDF
正文语种
中图分类基础医学;
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2. Safety and convenience of once-weekly somapacitan in adult GH deficiency: a 26-week randomized, controlled trial [J] . Gudmundur Johannsson, Ulla Feldt-Rasmussen, Ida Holme H?konsson, European journal of endocrinology . 2018,第5期

机译：成人每周GH缺乏的每周一次索马培他汀的安全性和便利性：一项为期26周的随机对照试验
3. Once-weekly Somapacitan is Effective and Well Tolerated in Adults with GH Deficiency: A Randomized Phase 3 Trial [J] . Gudmundur Johannsson, Murray B Gordon, Michael H?jby Rasmussen, The journal of clinical endocrinology and metabolism . 2020,第4期

机译：每周索皮肽曾经有效，在成人中耐受良好的GH缺乏：随机阶段3试验
4. Once-Weekly Somapacitan vs Daily GH in Children With GH Deficiency: Results From a Randomized Phase 2 Trial [J] . Lars S?vendahl, Tadej Battelino, Meryl Brod, The journal of clinical endocrinology and metabolism . 2020,第4期

机译：每周一次Somapacitan与GH缺乏的儿童每日GH：来自随机阶段2试验的结果
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7. MON-265 Once-Weekly Somapacitan in Japanese Adults with GH Deficiency Was Well Tolerated with Similar Efficacy to Daily GH: A Randomized Trial [O] . Fumio Otsuka, Yutaka Takahashi, Shigeyuki Tahara, 2020

机译：Mon-265每周265周次在日本成年人中嗜睡具有良好的GH缺乏良好的耐受性对每日GH类似的疗效：随机试验
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机译：Mon-265每周265周次在日本成年人中嗜睡，具有良好的GH缺乏良好的耐受性，对每日GH类似的疗效：随机试验

Safety and convenience of once-weekly somapacitan in adult GH deficiency: a 26-week randomized controlled trial

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