pH and temperature dual-sensitive liposome gel based on novel cleavable mPEG-Hz-CHEMS polymeric vaginal delivery system

机译：基于新型可裂解的mPEG-Hz-CHEMS聚合物阴道输送系统的pH和温度双敏感脂质体凝胶

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摘要

BackgroundIn this study, a pH and temperature dual-sensitive liposome gel based on a novel cleavable hydrazone-based pH-sensitive methoxy polyethylene glycol 2000-hydrazone-cholesteryl hemisuccinate (mPEG-Hz-CHEMS) polymer was used for vaginal administration.

机译：背景在这项研究中，基于新型可裂解基pH敏感的甲氧基聚乙二醇2000-hydr-胆固醇半琥珀酸酯（mPEG-Hz-CHEMS）聚合物的pH和温度双敏感脂质体凝胶用于阴道给药。

著录项

期刊名称 International Journal of Nanomedicine
作者
Daquan Chen; Kaoxiang Sun; Hongjie Mu; Mingtan Tang; Rongcai Liang; Aiping Wang; Shasha Zhou; Haijun Sun; Feng Zhao; Jianwen Yao; Wanhui Liu;
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作者单位

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年(卷),期 2012(7),-1
年度 2012
页码 2621–2630
总页数 10
原文格式 PDF
正文语种
中图分类生化遗传学;生化药理学;
关键词
mPEG-Hz-CHEMS polymer pH-sensitive liposomes thermosensitive liposome gel vaginal delivery;

机译：mPEG-Hz-CHEMS聚合物;pH敏感脂质体;热敏感;脂质体凝胶;阴道分娩;

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专利

1. pH and temperature dual-sensitive liposome gel based on novel cleavable mPEG-Hz-CHEMS polymeric vaginal delivery system [J] . Daquan Chen, Kaoxiang Sun, Hongjie Mu, International Journal of Nanomedicine . 2012,第2期

机译：基于新型可裂解的mPEG-Hz-CHEMS聚合物阴道输送系统的pH和温度双敏感脂质体凝胶
2. A new vaginal delivery system of amphotericin B: a dispersion of cationic liposomes in a thermosensitive gel. [J] . Kang JW, Davaa E, Kim YT, Journal of drug targeting . 2010,第8期

机译：两性霉素B的新阴道传递系统：阳离子脂质体在热敏凝胶中的分散体。
3. Novel local drug delivery system using thermoreversible gel in combination with polymeric microspheres or liposomes. [J] . Arai T, Benny O, Joki T, Anticancer Research: International Journal of Cancer Research and Treatment . 2010,第4期

机译：将热可逆凝胶与聚合物微球或脂质体结合使用的新型局部药物递送系统。
4. Poloxamer Gel for Delivery of Hydrophobic Drugs: - Effect of Commonly Used Additives onMicellization and Gelation of Poloxamer Based Drug Delivery System [C] . Ur-Rehman Tofeeq, Tavelin Staffan, Gr(o)bner Gerhard Annual meeting exposition of the Controlled Release Society . 2009

机译：泊洛沙姆凝胶用于疏水药物的递送：-常用添加剂对基于泊洛沙姆的药物递送系统的胶束化和胶凝作用的影响
5. Controlled delivery of therapeutic agents from polymer-based, in situ, gel-forming systems. [D] . Tang, Yu. 2008

机译：从基于聚合物的原位凝胶形成系统控制治疗剂的输送。
6. A high stable pH-temperature dual-sensitive liposome for tuning anticancer drug release [O] . Yilin Zhao, Fuli Cai, Xiangyi Shen, 2020

机译：高稳定的pH - 温度双敏脂质体用于调整抗癌药物释放
7. pH and temperature dual-sensitive liposome gel based on novel cleavable mPEG-Hz-CHEMS polymeric vaginal delivery system [O] . Chen, Daquan, Sun, Kaoxiang, Mu, Hongjie, 2012

机译：基于新型可裂解的mPEG-Hz-CHEMS聚合物阴道输送系统的pH和温度双敏感脂质体凝胶

pH and temperature dual-sensitive liposome gel based on novel cleavable mPEG-Hz-CHEMS polymeric vaginal delivery system

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