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Antiretroviral Treatment Adherence Rate and Associated Factors among People Living with HIV in Dubti Hospital Afar Regional State East Ethiopia

机译:东埃塞俄比亚阿法尔州杜布提医院艾滋病毒感染者的抗逆转录病毒治疗依从率及其相关因素

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摘要

Introduction. Antiretroviral Therapy has transformed HIV infection into a chronic manageable disease; it requires near perfect adherence rates (as high as 95%). In this study, we assessed antiretroviral treatment adherence rate and associated factors among people living with HIV in Dubti Hospital. Methods. A retrospective cross-sectional study design was conducted within February 1–30, 2014. All HIV-infected patients above the age of 18 years who took first line Antiretroviral Therapy were eligible for inclusion of the study. Adherence Scale was used for labeling patients as adherent or nonadherent. All HIV-infected patients record data were collected from the medical records, entered, and analyzed using Epi Info 7 and SPSS Version 20. Multivariable analysis was used to identify the relative effect of explanatory variables on low adherence rate. Results. A total of 370 patients aged 18 years and above, who started ART, were included in this study. The self-reported adherence rate of the patient on ART was 81.1%. Independent predictors of adherence were treatment duration. Conclusion. Adherence rate was associated with time to ART. That is, the longer they were on ART, the lesser they adhered.
机译:介绍。抗逆转录病毒疗法已将艾滋病毒感染转变为一种可控制的慢性疾病。它要求接近完美的遵守率(高达95%)。在这项研究中,我们评估了Dubti医院的HIV感染者的抗逆转录病毒治疗依从率和相关因素。方法。 2014年2月1日至30日进行了回顾性横断面研究设计。所有接受一线抗逆转录病毒疗法的18岁以上的HIV感染患者均符合纳入研究的条件。坚持量表用于将患者标记为依从或不依从。从病历中收集所有感染HIV的患者记录数据,使用Epi Info 7和SPSS Version 20进行输入和分析,使用多变量分析来确定解释变量对低依从性的相对影响。结果。这项研究共纳入了370位年龄在18岁以上的开始抗逆转录病毒治疗的患者。患者自我报告的抗逆转录病毒依从性为81.1%。依从性的独立预测因素是治疗持续时间。结论。坚持率与抗病毒治疗时间有关。也就是说,他们参加抗逆转录病毒疗法的时间越长,他们坚持的时间就越少。

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