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The Role of Cancer Boards in the Treatment Decisions Regarding Chemotherapy

机译:癌症委员会在有关化学疗法的治疗决策中的作用

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摘要

>Objective The influence of cancer boards with respect to the treatment decisions regarding chemotherapy remains to be elucidated. In the present study, we investigated the cases that presented at our institutional cancer boards, to assess the effect of cancer boards on the treatment decisions regarding chemotherapy. >Methods Data from the cancer boards at Yamagata University Hospital, Yamagata, Japan, were collected. Along with data from the clinical records, the details of the discussions and the chosen plan of treatment of the cancer boards were analyzed. >Results From February 2010 to February 2014, 1,541 cases were discussed at our cancer boards. Of these, 811 cases (52.6%) involved discussions about chemotherapy. Of those 811 cases, recommendations were made to alter the treatment plans for 189 cases (23.3%). The reasons for discouraging chemotherapy varied; however, 29/45 (64.4%) cases involved discouragement for the following reasons: old age, a comorbid condition, the physical (performance) status, or insufficient evidence to administer chemotherapy. Eighty-six patients were referred to the medical oncology department through the cancer boards. >Conclusion Our results showed that cancer boards have a great influence on the treatment decisions regarding chemotherapy and the prompt referral of cases to medical oncologists as necessary. In terms of future research, we will evaluate the effect of cancer boards on the prognosis and outcomes of cases using the institutional cancer registry.
机译:>目的尚需阐明癌症委员会对有关化学疗法的治疗决定的影响。在本研究中,我们调查了机构癌症委员会中提出的病例,以评估癌症委员会对化学疗法治疗决策的影响。 >方法收集了来自日本山形县山形大学医院癌症委员会的数据。连同临床记录中的数据一起,分析了讨论的细节和所选的癌症治疗方案。 >结果从2010年2月到2014年2月,我们的癌症委员会讨论了1,541例病例。其中811例(52.6%)涉及关于化学疗法的讨论。在这811例病例中,建议改变189例(23.3%)的治疗方案。阻止化疗的原因各不相同;然而,29/45(64.4%)的病例由于以下原因而灰心:老年,合并症,身体(表现)状况或缺乏足够的化学疗法证据。通过癌症委员会将86名患者转诊至肿瘤内科。 >结论我们的结果表明,癌症委员会对化学疗法的治疗决策有很大影响,并在必要时迅速将病例转诊给医学肿瘤学家。在未来的研究方面,我们将使用机构性癌症登记系统评估癌症委员会对病例预后和结果的影响。

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