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Basal Cell Carcinoma: A Single-Center Experience

机译:基底细胞癌:单中心经验

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摘要

Background. Basal cell carcinoma comprises the vast majority of skin cancers. It predominantly affects fair-skinned individuals, and its incidence is rising rapidly. Etiology may be multifactorial, but sun exposure appears to play a critical role. When detected early, the prognosis is excellent. Thus appropriate diagnosis, treatment, and surveillance are of utmost importance. Methods. From January 1994 to May 2012, 518 basal cell carcinomas were excised in our clinic. Data were collected retrospectively. Results. During 18-year period, 518 BCCs were excised from 486 patients. Most of the patients were males with a median age of 65.6 years. Most of the basal cell carcinomas were located in the head region. Nodular histological subtype dominated our series. Six percent of the excised lesions required reexcision because of involved margins. Our recurrence rate was 6.94% with the nose and the periauricular and periocular regions being the most common sites of occurrence. Conclusion. Although there is relatively low attributable mortality, the morbidity and cost of treatment are significant. A large body of information serves as a foundation for oncologic principles, diagnosis methods, surgical excisions, follow-up protocols, and reconstructive methodologies that are currently in use. Surgical ablation remains the mainstay of treatment.
机译:背景。基底细胞癌占皮肤癌的绝大多数。它主要影响皮肤白皙的个体,其发病率迅速上升。病因可能是多方面的,但是暴露在阳光下似乎起着关键作用。如果及早发现,则预后良好。因此,适当的诊断,治疗和监视至关重要。方法。从1994年1月至2012年5月,我们的诊所切除了518例基底细胞癌。回顾性收集数据。结果。在18年的时间里,从486例患者中切除了518个BCC。大多数患者是男性,中位年龄为65.6岁。大多数基底细胞癌位于头部区域。结节性组织学亚型主导我们的系列。切除的病灶中有6%由于边缘受累而需要切除。我们的复发率为6.94%,其中鼻子和耳周和眼周区域是最常见的发生部位。结论。尽管可归因的死亡率相对较低,但发病率和治疗费用却很可观。大量信息为当前使用的肿瘤学原理,诊断方法,手术切除,随访方案和重建方法奠定了基础。手术消融仍然是治疗的主要手段。

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