Development of Azo-Based Turn-On Chemical Array Systemfor Hydrazine Detection with Fluorescence Pattern Analysis

摘要

A facile turn-on chemical sensor array was developed for hydrazine detection by means of fluorescence pattern recognition. Taking advantage of the unique properties of the azo group, four different fluorogenic probes, Seoul-Fluor (SF)-Azo >01–>04, were designed and prepared. SF-Azo >01–>04 displayed fluorescence enhancement of up to 800-fold upon reaction with hydrazine, and all probes exhibited excellent selectivity in the presence of various anions and nucleophiles. By employing the probes in a cellulose paper-based array system, the hydrazine concentration was successfully determined by monitoring the change in fluorescent patterns.