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Creating Sustainable Biospecimen Resources in Medical Research

机译:在医学研究中创建可持续的生物标本资源

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摘要

BACKGROUND: Biospecimens collected during medical research and the data derived from these materials represent a valuable resource of genetic and genomic information that can be used in biopharmaceutical drug development. The growing industry trend towards personalized medicine combined with reductions in research funding is creating the need for organizations to focus on optimization of sample asset inventories and integration of high-quality sample bioprocessing methods in order to maximize future research and reduce costs.Many organizations have turned to smartsourcing strategies which leverage specialized outsourcing service partners to manage their sample assets due to the required investment in staff, technology, equipment and facilities. At its core, smartsourcing moves beyond the traditional “lift and shift” outsourcing philosophy to a more flexible “value by innovating” philosophy. Sample management smartsourcing strategies include offsite, onsite and hybrid models that can be integrated with sample bioprocessing to deliver incremental value. Biospecimen smartsourcing strategies are evolving to support organizations in achieving significant cost savings and research advancements. As such, the poster will detail the scientific and financial benefits of taking a strategic approach to sample management. Specifically, the poster will highlight: Various smartsourcing management models for centralized specimen storage, bioprocessing and data reconciliation. How to assess existing sample management processes to identify opportunities for improvements and cost-savings. Financial and scientific benefits of integrating sample management and bioprocessing solutions through smartsourcing partnerships. CONCLUSION: Sample management smartsourcing strategies challenge research organizations to not only focus on best practices in biobanking, but also to seek improvements in bioprocessing methodology, operating procedures, technology and data management. Organizations that manage research samples as valuable scientific assets achieve improved sample optimization and utilization throughout the discovery and development process, which enables them to invest in their R&D core competencies.
机译:背景:在医学研究期间收集的生物标本以及从这些材料中获得的数据代表了可用于生物制药药物开发的遗传和基因组信息的宝贵资源。个性化医学的行业趋势不断增长,加上研究经费的减少,使得组织需要集中精力优化样本资产库存并集成高质量的样本生物处理方法,以最大限度地利用未来的研究并降低成本。许多组织已经转向智能采购策略,由于需要对人员,技术,设备和设施进行投资,因此可以利用专业的外包服务合作伙伴来管理其样本资产。从本质上讲,智能外包已从传统的“提拔和转移”外包理念转变为更加灵活的“通过创新实现价值”理念。样品管理智能采购策略包括异地,现场和混合模型,这些模型可以与样品生物处理集成以提供增量价值。生物样本智能采购策略正在发展,以支持组织实现显着的成本节省和研究进步。因此,张贴者将详细介绍采取战略性方法进行样品管理的科学和财务利益。具体而言,海报将突出显示:用于集中式标本存储,生物处理和数据协调的各种智能采购管理模型。如何评估现有的样品管理流程,以确定改进和节省成本的机会。通过智能采购合作伙伴关系将样品管理和生物处理解决方案整合在一起的财务和科学收益。结论:样品管理的智能采购策略挑战研究组织不仅要关注生物银行的最佳实践,而且要寻求生物处理方法,操作程序,技术和数据管理方面的改进。将研究样品作为有价值的科学资产进行管理的组织可以在整个发现和开发过程中提高样品的优化和利用率,从而使他们能够投资于研发核心能力。

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