Optical Sensor Assistant with Voltage Enrichment forUltrasensitive Detection of Mercury Ions

摘要

Voltage enrichment-assisted surface-enhanced resonance Raman scattering (SERRS) was employed for monitoring mercury(II) ions based on a nanoporous gold (NPG)/aptamer hybrid sensor. The hybrid sensor based on the coordination chemistry of thymine–Hg²⁺–thymine interaction and an applied voltage that pushed mercury ions toward the NPG film improved both the speed and sensitivity of Hg²⁺ ion detection. The detection limit can reach 0.1 pM, even in the aqueous solution containing 13 metal ions, and the sensor also possesses a fine reproducibility and stability, promising great potential in real-time sensing applications.