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Low‐Dose Olanzapine Plus Granisetron and Dexamethasone for Carboplatin‐Induced Nausea and Vomiting in Patients with Thoracic Malignancies: A Prospective Multicenter Phase II Trial

机译：低剂量奥拉齐滨加上胸廓蛋白诱导的卡铂和胸腔恶性肿瘤患者呕吐的地塞洛顿和地塞米松：一项潜在的多中心第二期试验

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Olanzapine is an inexpensive and durable agent for the treatment of chemotherapy‐induced nausea and vomiting and is also superior to neurokinin‐1 receptor antagonists in the control of nausea. This study aimed to investigate the efficacy and safety of a low dose of 5 mg olanzapine plus granisetron and dexamethasone for treatment of carboplatin (CBDCA)‐induced nausea and vomiting in patients with thoracic malignancies.

机译：Olanzapine是一种廉价且耐用的药剂，用于治疗化疗诱导的恶心和呕吐，也优于神经激素-1受体拮抗剂在恶心的恶心。本研究旨在探讨低剂量的5毫克奥氮平和格兰司琼和地塞米松的疗效和安全性，用于治疗卡铂（CBDCA） - 胸部恶性肿瘤患者的恶心和呕吐。

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期刊名称 The Oncologist
作者
Chizuru Sakai; Mototsugu Shimokawa; Hirotoshi Iihara; Yukiyoshi Fujita; Shinnosuke Ikemura; Chiemi Hirose; Mie Kotake; Norihiko Funaguchi; Takenobu Gomyo; Hisao Imai; Jun Hakamata; Daizo Kaito; Koichi Minato; Takahiro Arai; Hitoshi Kawazoe; Akio Suzuki; Yasushi Ohno; Hiroyuki Okura;
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作者单位

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年(卷),期 2021(26),6
年度 2021
页码 e1066–e1072
总页数 7
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词

机译：胸部恶性肿瘤;奥拉扎丁;卡铂;恶心;呕吐;

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外文文献

1. Low-Dose Olanzapine Plus Granisetron and Dexamethasone for Carboplatin-Induced Nausea and Vomiting in Patients with Thoracic Malignancies: A Prospective Multicenter Phase II Trial [J] . Chizuru Sakai, Hisao Imai, Jun Hakamata, The oncologist . 2021,第6期

机译：低剂量奥拉扎丁加加granisetron和地塞米松，用于卡铂诱导的胸廓恶性肿瘤患者的恶心和呕吐：一个未来的多中心第二期试验
2. Efficacy and safety of 5 mg olanzapine combined with aprepitant, granisetron and dexamethasone to prevent carboplatin-induced nausea and vomiting in patients with gynecologic cancer: A multi-institution phase II study [J] . Iihara Hirotoshi, Shimokawa Mototsugu, Hayasaki Yoh, Gynecologic Oncology: An International Journal . 2020,第3期

机译：5毫克奥氮藻的功效和安全性联合用于治疗妇科癌症患者的卡铂诱导的恶心，呕吐：多机构期间II研究
3. Randomized, Placebo-Controlled, Phase III Trial of Fosaprepitant, Ondansetron, Dexamethasone (FOND) Versus FOND Plus Olanzapine (FOND-O) for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Patients with Hematologic Malignancies Receiving Highly Emetogenic Chemotherapy and Hematopoietic Cell Transplantation Regimens: The FOND-O Trial [J] . Amber B. Clemmons, Julianne Orr, Benjamin Andrick, Biology of blood and marrow transplantation: journal of the American Society for Blood and Marrow Transplantation . 2018,第10期

机译：随机，安慰剂对照，FosapRepitant，Ondansetron，Dexamethasone（喜欢的）与Fond Plus Olanzapine（FONE-O）进行血液学恶性肿瘤患者的血液学恶性肿瘤患者呕吐，ondansetron，ondansetron（Fond-O）的试验。接受高均匀化疗和造血细胞移植的血液学恶性肿瘤患者方案：FOND-O试验
4. A Prospective Multicenter Comparison Trial of Home Monitoring against Regular Follow-up in MADIT II Patients: Additional Visits and Cost Impact [C] . C. H. Elsner, P. Sommer, C. Piorkowski, Conference on Computers in Cardiology . 2006

机译：在MADIT II患者常规随访的预期多中心比较试验：额外访问和成本影响
5. Efficacy and safety of 5 mg olanzapine for nausea and vomiting management in cancer patients receiving carboplatin: integrated study of three prospective multicenter phase II trials [O] . Senri Yamamoto, Hirotoshi Iihara, Ryuji Uozumi, 2021

机译：癌症患者治疗癌症患者的疗效和安全性5毫克奥氮藻的疗效和安全性：三个前瞻性期二期试验的综合研究
6. Low‐Dose Olanzapine Plus Granisetron and Dexamethasone for Carboplatin‐Induced Nausea and Vomiting in Patients with Thoracic Malignancies: A Prospective Multicenter Phase II Trial [O] . Chizuru Sakai, Mototsugu Shimokawa, Hirotoshi Iihara, 2021

机译：低剂量奥拉齐滨加上胸廓蛋白诱导的卡铂和胸腔恶性肿瘤患者呕吐的地塞洛顿和地塞米松：一项潜在的多中心第二期试验

Low‐Dose Olanzapine Plus Granisetron and Dexamethasone for Carboplatin‐Induced Nausea and Vomiting in Patients with Thoracic Malignancies: A Prospective Multicenter Phase II Trial

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