Meta-inflammatory state and insulin resistance can improve after 10 weeks of combined all-extremity high-intensity interval training in sedentary overweight/obese females: a quasi-experimental study

摘要

Schematic design of the study. (a) A total of 86 sedentary females (18–25 years) with OW/OB interested to participate in this study. 15 out of 86 were excluded because of not meeting the age and BMI range. Following a verbal meeting, another 41 subjects were excluded as a result of meeting exclusion criteria including consuming specific medication, being on a diet, time conflict, any diagnosed diseases, participating in any training at least 6 months before this study, and smoking. The remaining 30 eligible individuals were allocated into two inactive (IG: n = 15, continued their regular diet and physical activities) and active (AG: n = 15, participating in the proposed combined HIIT) groups. Four subjects who uncompleted the training sessions or post-intervention procedures were omitted from the final statistical analysis. (b) Both groups underwent two blood sampling collection days. The pre-intervention sampling was conducted one week prior to the first training session and the post-intervention sampling approximately 48 h after the last training session. (c) The newly proposed all-extremity combined HIIT consisted of 4*4 min intervals separated by a 3-minutes active rest (lower-body cycling). Every four minutes’ interval consisted of a 45-sec all-extremity cycling followed by a 45-sec a lower-body or an upper-body resistance training alternatively. The intensity and volume of the training increased progressively based on the HRmax and 1RM percentage