Efficacy of Lactulose versus Senna Plus Ispaghula Husk Among Patients with Pre-Dialysis Chronic Kidney Disease and Constipation: A Randomized Controlled Trial

机译：乳糖与塞纳加患者患有透析前慢性肾疾病和便秘患者患者的乳糖和胰岛粥样菌株：随机对照试验

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摘要

Constipation is a common problem among patients with advanced chronic kidney disease (CKD), leading to a loss of quality of life. Pharmacologic treatments are in common use, but whether lactulose and senna plus ispaghula husk is effecive to treat constipation among patients with pre-dialysis CKD remains unknown.

机译：便秘是高级慢性肾病（CKD）患者的常见问题，导致生命质量丧失。药理治疗均常用，但乳糖和塞纳氏菌属叶片是否是治疗透析前CKD患者的便秘性的活性。

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期刊名称 International Journal of Nephrology and Renovascular Disease
作者
Naowanit Nata; Supaporn Suebsiripong; Bancha Satirapoj; Ouppatham Supasyndh; Amnart Chaiprasert;
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作者单位

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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 7
原文格式 PDF
正文语种
中图分类泌尿科学（泌尿生殖系疾病）;小儿泌尿科学;肾疾病;
关键词

机译：慢性肾病;乳糖;ispaghula稻;塞纳;便秘;

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1. Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease (BARACK D) trial–a multi-centre, prospective, randomised, open, blinded end-point, 36-month study of 2,616 patients within primary care with stage 3b chronic kidney disease to compare the efficacy of spironolactone 25?mg once daily in addition to routine care on mortality and cardiovascular outcomes versus routine care alone: study protocol for a randomized controlled trial [J] . Nathan R Hill, Daniel Lasserson, Ben Thompson, Trials . 2014,第1期

机译：醛固酮受体拮抗作用在慢性肾脏病（BARACK D）试验中的益处-一项多中心，前瞻性，随机，开放，盲点终点研究，为期3个月，研究对象为2,616名3b期慢性肾脏病初级保健患者，以比较螺内酯25毫克/天的常规治疗对死亡率和心血管疾病的疗效，与常规治疗相比，每天一次：随机对照试验的研究方案
2. Darbepoetin Alfa Versus Erythropoietin Alfa for Treatment of Renal Anemia in Patients with Chronic Kidney Disease at the Pre-Dialysis Stage: A Randomized Non-inferiority Trial [J] . Mehta KS, Sinha SD, Bandi Vamsi, Journal of the Association of Physicians of India . 2019,第1期

机译：Darbepoetin Alfa与促红细胞生成素Alfa治疗患有慢性肾脏疾病术前阶段的慢性肾病患者：随机的非劣级试验
3. Efficacy and safety of a crystalline lactulose preparation (SK-1202) in Japanese patients with chronic constipation: a randomized, double-blind, placebo-controlled, dose-finding study [J] . Kasugai Kunio, Iwai Hisakazu, Kuboyama Noboru, Journal of gastroenterology . 2019,第6期

机译：日本慢性便秘患者中的结晶乳糖制剂（SK-1202）的疗效和安全性：随机，双盲，安慰剂控制，剂量寻找研究
4. The Natural History of Chronic Kidney Disease Revisited-A 72-Month Mayo Health System Hypertension Clinic Practice-Based Research Network Prospective Report on End-Stage Renal Disease and Death Rates in 100 High-Risk Chronic Kidney Disease Patients: A Call for Circumspection [C] . Macaulay A.C. Onuigbo Conference on Peritoneal Dialysis . 2009

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6. Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease (BARACK D) trial–a multi-centre prospective randomised open blinded end-point 36-month study of 2616 patients within primary care with stage 3b chronic kidney disease to compare the efficacy of spironolactone 25 mg once daily in addition to routine care on mortality and cardiovascular outcomes versus routine care alone: study protocol for a randomized controlled trial [O] . Nathan R Hill, Daniel Lasserson, Ben Thompson, 2014

机译：醛固酮受体拮抗作用在慢性肾脏病（BARACK D）试验中的益处-一项多中心前瞻性随机开放盲点终点研究为期3个月研究对象为2616名3b期慢性肾脏病初级保健患者以比较螺内酯25 mg每日一次除常规治疗对死亡率和心血管结局的疗效与仅常规治疗相比：一项随机对照试验的研究方案
7. Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease (BARACK D) trial–a multi-centre, prospective, randomised, open, blinded end-point, 36-month study of 2,616 patients within primary care with stage 3b chronic kidney disease to compare the efficacy of spironolactone 25 mg once daily in addition to routine care on mortality and cardiovascular outcomes versus routine care alone: study protocol for a randomized controlled trial [O] . Hill, NR, Lasserson, D, Thompson, B, 2014

机译：醛固酮受体拮抗作用在慢性肾脏病（BARACK D）试验中的益处–一项多中心，前瞻性，随机，开放，盲点终点研究，为期3个月，研究对象为2,616名3b期慢性肾脏病初级保健患者，以比较螺内酯25 mg除常规治疗对死亡率和心血管结局的每日疗效与单独常规治疗相比，每天一次：随机对照试验的研究方案

Efficacy of Lactulose versus Senna Plus Ispaghula Husk Among Patients with Pre-Dialysis Chronic Kidney Disease and Constipation: A Randomized Controlled Trial

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