Abstract 27: Development Of A Novel Murine Distraction Device To Investigate Bone Regeneration In Long Bone Distraction Osteogenesis

摘要

Purpose: Distraction osteogenesis (DO) promotes endogenous bone formation across a mechanically controlled environment, providing anatomical and functional replacement of deficient tissue. The application of DO, to the appendicular skeleton, has revolutionized the treatment of many congenital and acquired defects. Here, we describe the development of a novel mouse distraction model for the tibia.