首页> 美国卫生研究院文献>Journal of Clinical and Experimental Hematopathology : JCEH >Welder’s pulmonary hemosiderosis associated with systemic iron overloadfollowing exacerbation of acute adult T-cell leukemia/lymphoma
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Welder’s pulmonary hemosiderosis associated with systemic iron overloadfollowing exacerbation of acute adult T-cell leukemia/lymphoma

机译:焊机的肺含铁血黄素沉着症与全身性铁超负荷有关急性成人T细胞白血病/淋巴瘤恶化后

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摘要

Herein, we describe a 61-year-old man diagnosed with pulmonary hemosiderosis following chemotherapy for acute adult T-cell leukemia/lymphoma (ATLL). Liver and heart biopsy confirmed hemosiderosis. ATLL progressed, and the patient died from multiorgan damage. Welder’s lung may have been involved in hemosiderosis and systemic iron overload. Abnormal iron metabolism or immune reactions may have influenced the clinical course, but these were not validated. Detailed analyses of family medical and lifestyle histories, and genetic examination should be performed in cases of systemic iron overload.
机译:本文中,我们描述了一名61岁的男性,在接受化疗后被诊断患有急性成人T细胞白血病/淋巴瘤(ATLL),并患有肺含铁血黄素沉着症。肝和心脏活检证实为铁血黄素沉着病。 ATLL进展,患者死于多器官损伤。焊工的肺可能与铁血黄素沉着症和全身性铁过剩有关。铁代谢异常或免疫反应可能影响了临床进程,但尚未得到证实。如果全身性铁超负荷,应详细分析家庭医疗和生活方式的历史,并进行基因检查。

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