Non-Motor Symptoms of the Postural Instability and Gait Difficulty Subtype in De Novo Parkinson’s Disease Patients: A Cross-Sectional Study in a Single Center

摘要

Little is known about non-motor symptoms (NMSs) associated with the postural instability and gait difficulty (PIGD) phenotype, especially in de novo Parkinson’s disease (PD) patients. The aims of this study were to compare NMSs between the tremor dominant (TD) and PIGD phenotypes in de novo PD patients and to determine factors that are associated with the PIGD subtype.