Author contributions: O.C., P.J.H., and J.M.G. designed the research questions; O.C. performed the research experiment; J.M.G. contributed unpublished reagents/analytic tools; O.C., P.J.H., and S.G.M. analyzed the data; O.C., and S.G.M. performed the computational simulations; O.C. wrote the paper; O.C., P.J.H., S.G.M., and J.M.G. approved the final version of the paper.
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