Keratoconus-susceptibility gene identification by corneal thickness genome-wide association study and artificial intelligence IBM Watson

摘要

The plot shows −log10-transformed P-values for all SNPs adjusted for age, sex, average axial length in both eyes, and the first principal component. The horizontal line represents the genome-wide significance threshold of 5.0 × 10−8, and the lower dashed line represents the threshold of 1.0 × 10−4 to identify candidate genes for Watson Drug Discovery analysis.