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Correction to: Novel sulphamoylated 2-methoxy estradiol derivatives inhibit breast cancer migration by disrupting microtubule turnover and organization

机译:矫正:通过破坏微管营业额和组织来校正:新型磺胺酰胺化2-甲氧基雌二醇衍生物抑制乳腺癌迁移

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摘要

Migration of interphase arrested cells is inhibited by ESE-15-one and ESE-one exposure. a MDA-MB-231 cells were first blocked in G1/S by exposure to thymidine before cell free zones were generated and cells were exposed to 0.2% DMSO, 0.5 μM ESE-15-one or 0.5 μM ESE-one. Cell migration into the cell-free zone was quantified after 18 h. The graph represents the average of at least three repeats with error bars representing SEM. *P < 0.001 in t-test comparison with DMSO-treated cells. b Light microscopy images of cell migration assays showing interphase cells at time 0 h and after 18 h treated with DMSO, ESE-15-one or ESE-one. Scale bar is 400 μm
机译:ISE-15-ONE和ESE-ONE暴露抑制了间止血细胞的迁移。在产生细胞自由区之前,首先在G1 / s中封闭MDA-MB-231细胞,并且在细胞的自由区暴露于0.2%DMS​​O,0.5μmeSE-15-1或0.5μm-one。在18小时后量化细胞迁移到无细胞区中。该图表示具有表示SEM的误差条的至少三个重复的平均值。 * P <0.001在与DMSO处理的细胞进行T检验比较。 B细胞迁移测定的光学显微镜图像显示在0小时和18小时后用DMSO,ESE-15-ONE或ESE-ON处理后18小时。秤杆为400μm

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