首页> 美国卫生研究院文献>BMC Cancer >Real-world efficacy and safety of two doses of cabazitaxel (20 or 25 mg/m2) in patients with castration-resistant prostate cancer: results of a Japanese post-marketing surveillance study
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Real-world efficacy and safety of two doses of cabazitaxel (20 or 25 mg/m2) in patients with castration-resistant prostate cancer: results of a Japanese post-marketing surveillance study

机译:抗阉割前列腺癌患者的两剂Cabazitaxel(20或25 mg / m2)的真实世界疗效和安全性:日本营销后监测研究的结果

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摘要

Patient disposition. *Patients who satisfied the following criteria: treatment with docetaxel before cabazitaxel; administration of prednisolone with cabazitaxel; and the cabazitaxel dose was not escalated above the initial dose during the treatment period. †Patients were matched using propensity scores on 17 factors: age, body surface area, duration of disease, Gleason score, T classification, N classification, M classification, ECOG PS, PSA, medical history, complications, curative intent focal therapy, palliative radiation therapy, switch from docetaxel, number of docetaxel treatment cycles, reason for discontinuation of docetaxel, and previous treatment with enzalutamide or abiraterone. C20, 20 mg/m2 cabazitaxel; C25, 25 mg/m2 cabazitaxel
机译:患者处置。 *满足以下标准的患者:在Cabazitaxel之前与多西紫杉醇进行治疗;用卡蓬松施用泼尼松龙;在治疗期间,卡蓬汀剂量在初始剂量之上没有升级。 △患者使用倾向分数匹配17因素:年龄,体表面积,疾病持续时间,Gleason得分,T分类,N分类,M分类,ECOG PS,PSA,病史,并发症,治疗意图焦点治疗,姑息辐射疗法,从多西紫杉醇切换,多发西紫杉醇治疗循环的数量,Docetaxel停止的原因,并用苯甲丁酰胺或Abiraaterone治疗。 C20,20 mg / m2 Cabazitax; C25,25 mg / m2 Cabazitaxel

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