The Effect of Mesenchymal Stem Cell Wharton’s Jelly on ADAMTS-4 and iNOS Levels in Osteoarthritis Rat Model

摘要

BACKGROUND:Osteoarthritis (OA) is one of the most common diseases among the elderly. OA occurs due to an imbalance between degradation and synthesis in articular joint tissue, causing changes in joint components such as cells, matrices and molecular production. Therefore, knowledge of cartilage-degrading enzymes such as ADAMTS-4 and iNOS is needed.