In the nose or on the tongue? Contrasting motivational effects of oral and intranasal oxytocin on arousal and reward during social processing

摘要

A The whole-brain voxel-wise analysis revealed a significant main effect of treatment in the right putamen reflecting that OT increased activation in this region relative to PLC (the cluster is presented in color, displayed at p < 0.05FWE); the overlaying mask in green represents the right putamen from the Brainnetome Atlas51 which was subsequently used as atlas-based independent region of interest (ROI) to extract beta-estimates for further analyses. B Group difference of OT concentration change. C Correlation between putamen activation to all faces and percentage concentration change of plasma oxytocin.