Translational stem cell therapy: vascularized skin grafts in skin repair and regeneration

摘要

A staged schematic of a traditional engineered skin graft implanted onto the injured skin. Autologous cells are first isolated from the patient’s biopsies and cultured to the desired confluency in vitro. The cells are then seeded onto a biocompatible scaffold in the presence of growth factors and cytokines that aid in the creation and maturation of a functional skin graft. The graft is subsequently implanted onto the wound area to aid in recovery and regeneration of the skin tissue