Quercetin attenuates the reduction of parvalbumin in middle cerebral artery occlusion animal model

摘要

Neurobehavioral scores (a), corner test (b), and proteomic analysis (c and d) of parvalbumin in vehicle + middle cerebral artery occlusion (MCAO), quercetin + MCAO, vehicle + sham, and quercetin + sham animals. Quercetin improves the neurological deficit score and tendency of turning towards to the right by ischemic stroke. Data (n = 16) are represented as the mean ± S.E.M. * p < 0.01, ** p < 0.05 vs. the vehicle + sham group, # p < 0.05 vs. vehicle + MCAO group. Squares indicate parvalbumin protein spots (c). Spot intensities were measured by PDQuest software. Spot intensities are reported as a ratio relative to vehicle + sham animals (d). Data (n = 4) are shown as means ± S.E.M. * p < 0.05. Mw and pI indicate molecular weight and isoelectric point, respectively