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An Open-label Single-arm Multicenter Feasibility Study Evaluating the Safety of Catheter-based Renal Denervation with DENEX™ in Patients with Uncontrolled Hypertension on Standard Medical Therapy

机译：一种开放标签单臂多中心可行性研究评估了在标准医学治疗的不受控制的高血压患者中对丹麦肾脏的安全性的肾脏消除的安全性

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摘要

DENEX™ is a novel renal sympathetic denervation (RDN) system that is equipped with 3 electrodes that deliver radiofrequency energy to the renal nerves along renal arteries. The purpose of this study was to evaluate the safety and efficacy of RDN with DENEX™ in resistant hypertension.

机译：DENEX™是一种新型肾交感神经剥离（RDN）系统，配备了3个电极，将射频能量提供给肾动脉的肾神经。本研究的目的是评估RDN在抗性高血压中具有DEAEX TM的安全性和功效。

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期刊名称 Korean Circulation Journal
作者
Chan Joon Kim; Kiyuk Chang; Byeong-Keuk Kim; Chang Gyu Park; Yangsoo Jang;
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作者单位

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年(卷),期 2021(51),1
年度 2021
页码 43–55
总页数 13
原文格式 PDF
正文语种
中图分类
关键词
Hypertension; Drug resistance; Denervation; Catheter ablation;

机译：高血压;耐药;去除;导管消融;

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专利

1. An Open-label, Single-arm, Multicenter Feasibility Study Evaluating the Safety of Catheter-based Renal Denervation with DENEX? in Patients with Uncontrolled Hypertension on Standard Medical Therapy [J] . Chan Joon Kim, Kiyuk Chang, Byeong-Keuk Kim, Korean Circulation Journal . 2021,第1期

机译：开放标签，单臂，多中心可行性研究评估了用DEAEX的导管肾脏剥离的安全性吗？在标准医疗治疗的不受控制的高血压患者中
2. I-COMBINE Study: Assessment of Efficacy and Safety Profile of Irbesartan/Amlodipine Fixed-Dose Combination Therapy Compared With Amlodipine Monotherapy in Hypertensive Patients Uncontrolled With Amlodipine 5 mg Monotherapy: A Multicenter, Phase III, Prospective, Randomized, Open-Label With Blinded-End Point Evaluation Study [J] . BobrieG. Clinical therapeutics . 2012,第8期

机译：I-COMBINE研究：厄贝沙坦/氨氯地平固定剂量联合疗法与氨氯地平单药治疗在未经氨氯地平5 mg单药治疗的高血压患者中的疗效和安全性评估：多中心，III期，前瞻性，随机，开放标签，盲法终点评估研究
3. I-ADD Study: Assessment of Efficacy and Safety Profile of Irbesartan/Amlodipine Fixed-Dose Combination Therapy Compared With Irbesartan Monotherapy in Hypertensive Patients Uncontrolled With Irbesartan 150 mg Monotherapy: A Multicenter, Phase III, Prospective, Randomized, Open-Label With Blinded-End Point Evaluation Study [J] . BobrieG. Clinical therapeutics . 2012,第8期

机译：I-ADD研究：厄贝沙坦/氨氯地平固定剂量联合治疗与厄贝沙坦单药治疗与未经厄贝沙坦150毫克单药治疗的高血压患者的疗效和安全性评估：多中心，III期，前瞻性，随机，开放标签，盲法终点评估研究
4. Safety of Echocardiographic Contrast in Hospitalized Patients with Pulmonary Hypertension: A Multicenter Study [C] . Suma V., Wever-Pinzon O., Ahuja A., World Congress on Heart Disease. . 2013

机译：住院肺动脉高压患者超声心动图的安全性：多中心研究
5. Developing a study to evaluate the impact of a goal-oriented, protocol-driven program with home telemonitoring on the blood pressure of type 2 diabetic patients with uncontrolled hypertension. [D] . Al-Suwaida, Kerrayem Omer. 2003

机译：开展一项研究，以评估一项以目标为导向，由协议驱动的程序进行家庭远程监控对2型糖尿病高血压患者的血压的影响。
6. ReferencesEfficiency and safety of renal denervation via cryoablation (Cryo-RDN) in Chinese patients with uncontrolled hypertension: study protocol for a randomized controlled trial [O] . Han Chen, Meng Ji, Yi Zhang, 2019

机译：中国非控制性高血压患者经冷冻消融术（Cryo-RDN）进行肾神经支配的效率和安全性：一项随机对照试验的研究方案
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An Open-label Single-arm Multicenter Feasibility Study Evaluating the Safety of Catheter-based Renal Denervation with DENEX™ in Patients with Uncontrolled Hypertension on Standard Medical Therapy

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