首页> 美国卫生研究院文献>Journal of Hematology Oncology >Fifth-week immunogenicity and safety of anti-SARS-CoV-2 BNT162b2 vaccine in patients with multiple myeloma and myeloproliferative malignancies on active treatment: preliminary data from a single institution
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Fifth-week immunogenicity and safety of anti-SARS-CoV-2 BNT162b2 vaccine in patients with multiple myeloma and myeloproliferative malignancies on active treatment: preliminary data from a single institution

机译:五个周免疫原性和抗SARS-COV-2 BNT162B2患者的免疫原性和安全性患有多发性骨髓瘤和肌酚的活性治疗患者的疫苗:单一机构的初步数据

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摘要

Participants flow diagram. *Fifteen MM patients were excluded from analysis at TP0 due to refusal of the study (n = 12) or no systemic ongoing therapy (n = 3; one patient on radiotherapy and two on follow-up post-VMP). **One MM patient did not receive the second dose due to concomitant bacterial infection. ***Three MM patients did not perform titration at TP2. §Three CML patients were excluded from analysis at TP0 due to refusal of the study (n = 2) or anti-SARS-CoV-2 IgG positivity at basal (n = 1). §§One CML patient did not receive the second dose because lost to follow-up. ^Fourteen MPN patients were excluded from analysis at TP0 due to refusal of the study (n = 12), no systemic ongoing therapy (n = 1) or anti-SARS-CoV-2 IgG positivity at basal (n = 1). ^^Two MPN patients did not perform titration at TP2
机译:参与者流程图。 *由于研究(n = 12)拒绝(n = 12)或没有全身持续治疗(n = 3;放射治疗的一名患者和在后续后续后的两种患者的情况下,患者不包括在TP0的分析中被排除在TP0的分析之外。 **由于伴随的细菌感染,一个mm患者未接收第二剂。 ***三毫米患者在TP2下没有进行滴定。 §ThreeCML患者由于基础(n = 1)的研究(n = 2)或抗SARS-COV-2 IgG阳性而被排除在TP0的分析之外。 §§OneCML患者没有收到第二剂,因为丢失了跟进。 ^由于研究的拒绝(n = 12),14例MPN患者被排除在TP0的分析之外,没有全身持续治疗(N = 1)或基底(n = 1)的抗SARS-COV-2 IgG阳性。 ^^两种MPN患者在TP2没有进行滴定

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