Reducing Fungal Exposure Critical for Treating Rhinosinusitis with or without Polyps Letter

摘要

I read with great interest your recent fascinating 2021 review by Bachert et al on chronic rhinosinusitis with nasal polyps.1 The paper succinctly notes that chronic rhinosinusitis is common, has high economic and human costs, has many recurrences, and is often difficult to treat with conventional drug or surgical treatments. While I think the paper was generally well written and interesting, I think much more emphasis should have been placed on the importance of molds, mycotoxins, bacteria, and other bioaerosols on the development of rhinosinusitis with or without polyps. The authors state that “no specific genetic or environmental factors are strongly associated with the disorder.”