Ocular complications following intravitreal bevacizumab injection for retinopathy of prematurity and assessment of risk factors

摘要

Left eye of a patient (gestational age: 28 weeks, birth weight: 1000 g) with retinopathy of prematurity (a and b: zone 1, stage3 confluent intravitreal neovascularization and plus disease). Intravitreal Bevacizumab was injected in this eye. The plus disease was improved significantly (c), and neovascularization also reduced. The traction increased in the supranasal part of the retina (d). Laser photocoagulation of the avascular area was done (e and f), and the traction increased 7 weeks after laser (g). Re-injection of intravitreal Bevacizumab was performed. Parents of the patient have not accepted vitrectomy. Finally, the crunch phenomenon occurred (h)