A novel germline mutation in hMLH1 in three Korean women with endometrial cancer in a family of Lynch syndrome: case report and literature review

摘要

Pedigree of the family with Lynch syndrome. (Square, male; circle, female; oblique line, deceased;?, unknown; black, disease; dumber, diagnosed/age at diagnose; arrow, the proband; +, proven mutation carrier; −, non-mutation carrier) Not all relatives consented to undergo genetic screening