Endoscopy in Extraesophageal Manifestations Secondary to Gastroesophageal Reflux Disease: Why Do We Insist?

摘要

The concept of extraesophageal manifestations secondary to gastroesophageal reflux disease (GERD) is complex and not always clear. Although several extra­esophageal symptoms have been associated with GERD, only asthma, cough, and hoarseness have evidence-based support [1]. The role of upper gastrointestinal endoscopy (UGIE) in GERD is that of screening in certain high-risk groups in particular overweight white males with chronic GERD symptoms and aged >50 years [2]. In the context of suspected extraesophageal manifestations of GERD, UGIE has a low diagnostic yield and therefore poor predictive value for determination of GERD as the cause of these symptoms [1]. However, despite the foregoing, UGIE is still frequently requested and little is known about endoscopic findings in this context.