Trehalose induces SQSTM1/p62 expression and enhances lysosomal activity and antioxidative capacity in adipocytes

摘要

Trehalose is a disaccharide reported to ameliorate adipocyte hypertrophy and improve metabolic state. The present study demonstrated that trehalose augments the levels of SQSTM1, lysosome‐related factors and antioxidative factors, which induces lysosomal activity and antioxidative capacity in adipocytes. These observations reveal a mechanism for the above effects of trehalose.