Dementia and associated cognitive decline, as well as age-related neurodegenerative diseases, lead to a drastic reduction in quality of life in later years and are some of the greatest and most urgent public health issues facing Western societies today. Despite the projected increase in age-associated dementia (three-fold by 2060), there is lack of effective disease-modifying treatments and no established lifestyle guidelines for preventing and/or delaying dementia [1]. Yet, modifiable risk factors (e.g. such as diet, physical fitness), can account for as much as 35% of the dementia burden later in life [2].
展开▼
