Detection of BCR/ABL Translocation in Bone Marrow Derived Mesenchymal Stem Cells in Egyptian CML Patients

机译：埃及CML患者骨髓源间充质干细胞中BCR / ABL易位的检测

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BACKGROUND:Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of hematopoietic stem cells. It is characterized at the cytogenetic level by Philadelphia (ph) chromosome and at the molecular level by the BCR/ABL gene rearrangement. Bone marrow derived mesenchymal stem cells (MSCs) are pluripotent stem cells that can differentiate into several mesenchymal tissues.

机译：背景：慢性粒细胞白血病（CML）是造血干细胞的克隆性骨髓增生性疾病。通过费城（ph）染色体在细胞遗传学水平上进行表征，并通过BCR / ABL基因重排在分子水平上进行表征。骨髓来源的间充质干细胞（MSC）是多能干细胞，可以分化为几种间充质组织。

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期刊名称 Open Access Macedonian Journal of Medical Sciences
作者
Taghrid Mohamed Gaafar; Inas Ismail Raafat; Azza Ahmed Aly; Nagwa Abd EL-Ghaffar Mohamed; Reem Jan Farid; Neveen Ezzat Saad; Rabab EL-Hawary; Naglaa Mostafaa; Mirhan Mohamed Ahmed;
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年(卷),期 2015(3),2
年度 2015
页码 231–236
总页数 6
原文格式 PDF
正文语种
中图分类
关键词
Chronic myeloid leukemia mesenchymal stem cell Philadelphia chromosome;

机译：慢性粒细胞白血病;间充质干细胞;费城染色体;

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1. Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells [J] . Christopher S. Chen, Grace L. Lin, Jeroen Eyckmans Biology Open . 2012,第11期

机译：人骨髓和骨膜来源的祖细胞的间充质干细胞的粘附和机械调节人骨髓和骨膜来源的祖细胞的间质干细胞分化的粘附和机械调控人骨间质干细胞分化的粘附和机械调控骨髓和骨膜来源的祖细胞
2. Mesenchymal stem cells from patients with chronic myeloid leukemia do not express BCR-ABL and have absence of chimerism after allogeneic bone marrow transplant [J] . Carrara R.C.V., Orellana M.D., Fontes A.M., Brazilian Journal of Medical and Biological Research . 2007,第1期

机译：同种异体骨髓移植后，来自慢性粒细胞白血病患者的间充质干细胞不表达BCR-ABL，并且缺乏嵌合
3. Mesenchymal stem cells from patients with chronic myeloid leukemia do not express BCR-ABL and have absence of chimerism after allogeneic bone marrow transplant [J] . A.m. Fontes, D.t. Covas, J.c. Voltarelli, Brazilian Journal of Medical and Biological Research . 2007,第1期

机译：同种异体骨髓移植后，来自慢性粒细胞白血病患者的间充质干细胞不表达BCR-ABL，并且缺乏嵌合
4. In Vivo Osteogenic Potential of Mesenchymal Stromal Cells Derived From Patient'S Bone Marrow on Hydroxyapatite Ceramics [C] . Asako Matsushima, Noriko Kotobuki, Hiroko Machida, Bioceramics . 2007

机译：羟基磷灰石陶瓷上源自患者骨髓的间充质基质细胞的体内成骨潜能
5. Comparison of Platelet-rich Plasma, Bone Marrow Mesenchymal Stem Cells, Adipose-derived Mesenchymal Stem Cells, and Placebo in the Treatment of Knee Osteoarthritis [D] . Bach, Oscar. 2020

机译：富含血小板血浆，骨髓间充质干细胞，脂肪衍生间充质干细胞，安慰剂治疗膝关节骨关节炎的比较
6. BCR-ABL1-positive microvesicles malignantly transform human bone marrow mesenchymal stem cells in vitro [O] . Fen-fen Fu, Xiao-jian Zhu, Hong-xiang Wang, 2017

机译：BCR-ABL1阳性微泡在体外恶性转化人骨髓间充质干细胞
7. Detection of BCR/ABL Translocation in Bone Marrow Derived Mesenchymal Stem Cells in Egyptian CML Patients [O] . Gaafar Taghrid Mohamed, Raafat Inas Ismail, Aly Azza Ahmed, 2015

机译：埃及CML患者骨髓源间充质干细胞中BCR / ABL易位的检测

Detection of BCR/ABL Translocation in Bone Marrow Derived Mesenchymal Stem Cells in Egyptian CML Patients

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