Iron-Uptake Systems of Chicken-Associated Salmonella Serovars and Their Role in Colonizing the Avian Host

摘要

Iron is an essential micronutrient for most bacteria. strains, representing human and animal pathogens, have adopted several mechanisms to sequester iron from the environment depending on availability and source. Chickens act as a major reservoir for strains which can lead to outbreaks of human salmonellosis. In this review article we summarize the current understanding of the contribution of iron-uptake systems to the virulence of non-typhoidal strains in colonizing chickens. We aim to address the gap in knowledge in this field, to help understand and define the interactions between and these important hosts, in comparison to mammalian models.