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Fe Porphyrin-Based SOD Mimic and Redox-Active Compound (OH)FeTnHex-2-PyP4+ in a Rodent Ischemic Stroke (MCAO) Model: Efficacy and Pharmacokinetics as Compared to Its Mn Analogue (H2O)MnTnHex-2-PyP5+

机译：啮齿动物缺血性中风（MCAO）模型中基于铁卟啉的SOD模拟和氧化还原活性化合物（OH）FeTnHex-2-PyP4 +：与Mn类似物（H2O）MnTnHex-2-PyP5 +相比的功效和药代动力学

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期刊名称 Antioxidants
作者
Litao Li; Artak Tovmasyan; Huaxin Sheng; Bin Xu; Romulo S. Sampaio; Julio S. Reboucas; David S. Warner; Ines Batinic-Haberle; Ivan Spasojevic;
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作者单位

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年(卷),期 2020(9),6
年度 2020
页码 -1
总页数 16
原文格式 PDF
正文语种
中图分类分子生物学;
关键词
MnTnHex-2-PyP;

机译：MnTnHex-2-PyP;

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外文文献

1. Mn porphyrin-based SOD mimic, MnTnHex-2-PyP5+, and non-SOD mimic, MnTBAP(3-), suppressed rat spinal cord ischemia/reperfusion injury via NF-kappa B pathways [J] . Celic T., Spanjol J., Bobinac M., Free radical research . 2014,第1a12期

机译：基于锰卟啉的SOD模拟物MnTnHex-2-PyP5 +和非SOD模拟物MnTBAP（3-）通过NF-κB途径抑制大鼠脊髓缺血/再灌注损伤
2. Redox-Active Mn Porphyrin-based Potent SOD Mimic, MnTnBuOE-2-PyP5+, Enhances Carbenoxolone-Mediated TRAIL-Induced Apoptosis in Glioblastoma Multiforme [J] . Yulyana Yulyana, Tovmasyan Artak, Ho Ivy A. W., Stem cell reviews and Reports . 2016,第1期

机译：氧化还原活性锰卟啉为基础的强效SOD模拟物MnTnBuOE-2-PyP5 +增强了羧苄酮介导的TRAIL诱导的胶质母细胞瘤的凋亡。
3. Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP~(5+) and MnTnHex-2-PyP~(5+) [J] . Tin Weitner, Ivan Kos, Huaxin Sheng, Free Radical Biology and Medicine: The Official Journal of the Oxygen Society . 2013,第May期

机译：两种基于卟啉的Mn超氧化物歧化酶模拟物MnTE-2-PyP〜（5+）和MnTnHex-2-PyP〜（5+）的综合药代动力学研究和口服生物利用度
4. Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics MnTE-2-PyP5+ and MnTnHex-2-PyP5+ [O] . Tin Weitner, Ivan Kos, Huaxin Sheng, -1

机译：综合药代动力学研究和两种Mn卟啉的SOD模拟物MNTe-2-PYP5 +和MNTNHEX-2-PYP5 +的综合药代动力学研究和口服生物利用度
5. Fe Porphyrin-Based SOD Mimic and Redox-Active Compound, (OH)FeTnHex-2-PyP4+, in a Rodent Ischemic Stroke (MCAO) Model: Efficacy and Pharmacokinetics as Compared to Its Mn Analogue, (H2O)MnTnHex-2-PyP5+ [O] . Litao Li, Artak Tovmasyan, Huaxin Sheng, 2020

机译：基于Fe Poryrin的SOD模拟和氧化还原活性化合物，（OH）FETNHEX-2-PYP4 +，啮齿动物缺血性卒中（MCAO）模型：疗效和药代动力学与其Mn类似物相比，（H2O）MNTNHEX-2-PYP5 +

Fe Porphyrin-Based SOD Mimic and Redox-Active Compound (OH)FeTnHex-2-PyP4+ in a Rodent Ischemic Stroke (MCAO) Model: Efficacy and Pharmacokinetics as Compared to Its Mn Analogue (H2O)MnTnHex-2-PyP5+

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