Gardenia jasminoides extract and its constituent genipin inhibit activation of CD3/CD28 co-stimulated CD4+ T cells via ORAI1 channel

机译：茉莉子提取物及其成分genipin通过ORAI1通道抑制CD3 / CD28共刺激的CD4 + T细胞的活化

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期刊名称 The Korean Journal of Physiology Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology
作者
Hyun Jong Kim; Yu Ran Nam; JooHan Woo; Woo Kyung Kim; Joo Hyun Nam;
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作者单位

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年(卷),期 2020(24),4
年度 2020
页码 -1
总页数 10
原文格式 PDF
正文语种
中图分类药学;人体生理学;
关键词
CD4 positive T lymphocytes; Gardenia; Genipin; Interleukin-2; ORAI1 protein;

机译：CD4阳性T淋巴细胞;G子;Genipin;Interleukin-2;ORAI1蛋白;

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专利

1. Gardenia jasminoides extract and its constituent, genipin, inhibit activation of CD3/CD28 co-stimulated CD4 T cells via ORAI1 channel [J] . Hyun Jong Kim, Yu Ran Nam, JooHan Woo, The Korean Journal of Physiology & Pharmacology . 2020,第4期

机译：Gardenia Jasminoides提取物及其成分，Genipin，通过ORAI1通道抑制CD3 / CD28共刺激的CD4 T细胞的激活
2. Genipin, a constituent of Gardenia jasminoides Ellis, induces apoptosis and inhibits invasion in MDA-MB-231 breast cancer cells. [J] . Kim ES, Jeong CS, Moon A Oncology reports . 2012,第2期

机译：Genipin是茉莉El子的成分，可诱导细胞凋亡并抑制MDA-MB-231乳腺癌细胞的侵袭。
3. CD3/CD28 Co-Stimulated Activation of PI3K-mTORC2-AKT Metabolic Programming Augments Granzyme B Expression and Direct Cytotoxicity in Expanded Human iNKT Cells [J] . Klein-Geltink Ramon I., de Araujo Claudia A. Alves, Andrews Kelly A., Biology of blood and marrow transplantation: journal of the American Society for Blood and Marrow Transplantation . 2015,第2Suppla1期

机译：CD3 / CD28共同刺激PI3K-mTORC2-AKT代谢程序设计的激活，增强了人iNKT细胞中粒酶B的表达和直接的细胞毒性。
4. OPTIMIZED PROCESS FOR REGULATORY T CELL ACTIVATION AND EXPANSION USING DYNABEADS~(TM) TREG CD3/CD28 FOR CLINICAL APPLICATIONS [C] . Hui Zhang, Kerstin Bernstrom, Nora Lieske, Scale-up and manufacturing of cell-based therapies V . 2017

机译：使用DYNABEADS〜（TM）TREG CD3 / CD28进行调节性T细胞活化和扩增的最佳方法，用于临床应用
5. Vaccine delivered HIV envelope inhibits CD4+ T cell activation: A mechanism for poor HIV vaccine responses. [D] . Fernando, Kathy P. 2006

机译：疫苗递送的HIV包膜抑制CD4 + T细胞活化：一种不良的HIV疫苗反应机制。
6. Gardenia jasminoides extracts and gallic acid inhibit lipopolysaccharide-induced inflammation by suppression of JNK2/1 signaling pathways in BV-2 cells [O] . Wen-Hung Lin, Heng-Hung Kuo, Li-Hsing Ho, 2015

机译：子提取物和没食子酸通过抑制BV-2细胞中JNK2 / 1信号通路抑制脂多糖诱导的炎症
7. Gardenia jasminoides extract and its constituent, genipin, inhibit activation of CD3/CD28 co-stimulated CD4+ T cells via ORAI1 channel [O] . Hyun Jong Kim, Yu Ran Nam, JooHan Woo, 2020

机译：Gardenia Jasminoides提取物及其成分，Genipin，通过ORAI1通道抑制CD3 / CD28共刺激的CD4 + T细胞的活化
8. Costimulation of T Cell Receptor/CD3-Mediated Activation of Resting Human CD4+ TCells by Leukocyte Function-Associated Antigen-1 Ligand Intercellular Cell Adhesion Molecule-1 Involves Prolonged Inositol Phospholipid Hydrolysis and Sustained Increase of In [R] . Van Seventer, G. A., Bonvini, E., Yamada, H., 1992

机译：白细胞功能相关抗原-1配体细胞间粘附分子-1的T细胞受体/ CD3介导的静息人CD4 + TCell活化共刺激涉及延长的肌醇磷脂水解和持续增加的In

Gardenia jasminoides extract and its constituent genipin inhibit activation of CD3/CD28 co-stimulated CD4+ T cells via ORAI1 channel

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