Maximal haemostatic effect is attained in porcine skin within 7 min of the administration of a local anaesthetic together with epinephrine refuting the need for a 30 min waiting time

摘要

Based on clinical experience gained over many years, the maximal haemostatic effect following administration of local anaesthetics containing epinephrine is generally believed to occur within 10 min. Surprisingly, it was found in a recent study, in which bleeding was quantified intraoperatively, that maximal haemostasis did not occur until 30 min. If this is indeed the case, then it would be necessary to extend the preoperative waiting time to minimize perioperative bleeding.