Phase III placebo-controlled randomized double-blind trial of tableted therapeutic TB vaccine (V7) containing heat-killed M. vaccae administered daily for one month

机译：含安慰剂的TB型治疗性平板疫苗（V7）的第三阶段安慰剂对照随机双盲试验其中包含每天服用热灭活的M. vaccae的疫苗持续一个月

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Immunotherapy of tuberculosis (TB) to shorten treatment duration represents an unmet medical need. Orally delivered, tableted TB vaccine (V7) containing heat-killed (NCTC 11659) has been demonstrated in prior clinical studies to be safe and fast-acting immune adjunct.

机译：结核病（TB）的免疫疗法可缩短治疗时间，这是医疗需求未得到满足的原因。在先前的临床研究中已经证明，口服递送的含热灭活的片剂TB疫苗（V7）（NCTC 11659）是安全，速效的免疫佐剂。

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期刊名称 Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
作者
Aldar S. Bourinbaiar; Uyanga Batbold; Yuri Efremenko; Munkhburam Sanjagdorj; Dmytro Butov; Narantsetseg Damdinpurev; Elena Grinishina; Otgonbayar Mijiddorj; Mikola Kovolev; Khaliunaa Baasanjav; Tetyana Butova; Natalia Prihoda; Ochirbat Batbold; Larisa Yurchenko; Ariungerel Tseveendorj; Olga Arzhanova; Erkhemtsetseg Chunt; Hanna Stepanenko; Nina Sokolenko; Natalia Makeeva; Marina Tarakanovskaya; Vika Borisova; Alan Reid; Valeryi Kalashnikov; Peter Nyasulu; Satria A. Prabowo; Vichai Jirathitikal; Allen I. Bain; Cynthia Stanford; John Stanford;
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年(卷),期 2020(18),-1
年度 2020
页码 -1
总页数 8
原文格式 PDF
正文语种
中图分类生理学;
关键词
MDR; XDR; Immunotherapy; Therapeutic vaccine;

机译：耐多药;XDR;免疫治疗;治疗性疫苗;

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1. Randomized, placebo-controlled Phase II trial of heat-killed Mycobacterium vaccae (Immodulon batch) formulated as an oral pill (V7) [J] . ButovD.A., EfremenkoY.V., PrihodaN.D., Immunotherapy . 2013,第10期

机译：配制为口服药（V7）的热灭活的牛分枝杆菌（Immodulon批次）的随机，安慰剂对照II期临床试验
2. Randomized, placebo-controlled phase II trial of heat-killed Mycobacterium vaccae (Longcom batch) formulated as an oral pill (V7) [J] . EfremenkoY.V., ButovD.A., PrihodaN.D., Human vaccines & immunotherapeutics. . 2013,第9期

机译：配制为口服药（V7）的热灭活牛分枝杆菌（Longcom批次）的随机，安慰剂对照II期临床试验
3. 300?Final analysis of a prospective, randomized, double-blind, placebo-controlled phase IIb trial of tumor lysate, particle-loaded, dendritic cell vaccine in stage III/IV melanoma: 36-month analysis [J] . Lexy Adams, Robert Chick, Guy Clifton, Journal for ImmunoTherapy of Cancer . 2020,第Suppla3期

机译：300？最终分析肿瘤裂解物的前瞻性，随机，双盲，安慰剂对照相IIB试验，III / IV黑色素瘤中颗粒裂解，树突细胞疫苗：36个月分析
4. A double-blind, randomized phase II trial of thesafety and immunogenicity of 26-valent group A streptococcus vaccine in healthy adults [C] . Shelly A. McNeil, Scott A. Halperin, Joanne M. Langley, Lancefield International Symposium on Streptococci and Streptococcal Diseases . 2006

机译：一种双盲，随机期II试验，对健康成人的26岁的26岁群体的疫苗疫苗
5. A Phase II, Randomized, Double-Blind, Placebo-Controlled Trial of Fish Oil (Eicosapentaenoic Acid and Docosahexaenoic Acid) on Lung and Systemic Inflammation in Patients with Acute Lung Injury. [D] . Stapleton, Renee Doney. 2010

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6. Randomized, placebo-controlled phase II trial of heat-killed Mycobacterium vaccae (Longcom batch) formulated as an oral pill (V7) [O] . Yuri V Efremenko, Dmytro A Butov, Natalia D Prihoda, 2017

机译：配制为口服药（V7）的热灭活牛分枝杆菌（Longcom批次）的随机，安慰剂对照II期临床试验
7. 300 Final analysis of a prospective, randomized, double-blind, placebo-controlled phase IIb trial of tumor lysate, particle-loaded, dendritic cell vaccine in stage III/IV melanoma: 36-month analysis [O] . Lexy Adams, Robert Chick, Guy Clifton, 2020

机译：300末期分析肿瘤裂解物的前瞻性，随机，双盲，安慰剂对照相IIB试验，颗粒裂解，树突细胞疫苗III / IV黑色素瘤：36个月分析

Phase III placebo-controlled randomized double-blind trial of tableted therapeutic TB vaccine (V7) containing heat-killed M. vaccae administered daily for one month

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