Greater BOLD response to working memory in endurance‐trained adults revealed by breath‐hold calibration

摘要

Cardiorespiratory fitness is associated with increased frontal and parietal activation during executive function tasks. While these findings suggest fitness‐related enhancement of neuronal response, the utility of functional magnetic resonance imaging (fMRI) may be limited by potential fitness‐related differences in global vascular reactivity. The aim of this study was to determine if highly fit adults display differential activation during working memory after calibration for vascular reactivity relative to their sedentary counterparts.