Gene–disease association study of tumor necrosis factor‐α G‐308A gene polymorphism with risk of major depressive disorder: A systematic review and meta‐analysis

摘要

The single nucleotide polymorphism (SNP) of the tumor necrosis factor‐α (TNF‐α) G‐308A gene is the most studied regarding susceptibility to major depressive disorder (MDD). However, results have been controversial perhaps due to the heterogeneous genetic backgrounds influenced by race as well as subtypes of depression.