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Phase II Trial of Cediranib in Combination With Cisplatin and Pemetrexed in Chemotherapy-Naïve Patients With Unresectable Malignant Pleural Mesothelioma (SWOG S0905)

机译：Cediranib联合顺铂和培美曲塞的II期试验在未接受化疗的未切除恶性胸膜间皮瘤患者中的治疗（SWOG S0905）

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摘要

Antiangiogenic agents combined with chemotherapy have efficacy in the treatment of unresectable malignant pleural mesothelioma (MPM). Cediranib (AstraZeneca, Cheshire, United Kingdom), a vascular endothelial growth factor receptor and platelet-derived growth factor receptor inhibitor, demonstrated therapeutic potential in a prior phase I trial. We evaluated a phase II trial for efficacy.

机译：抗血管生成剂联合化学疗法可治疗不可切除的恶性胸膜间皮瘤（MPM）。 Cediranib（阿斯利康，英国柴郡）是一种血管内皮生长因子受体和血小板衍生的生长因子受体抑制剂，在先前的I期试验中显示出治疗潜力。我们评估了II期临床试验的疗效。

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期刊名称 Journal of Clinical Oncology
作者
Anne S. Tsao; Jieling Miao; Ignacio I. Wistuba; Nicholas J. Vogelzang; John V. Heymach; Frank V. Fossella; Charles Lu; Mario R. Velasco; Brandy Box-Noriega; James G. Hueftle; Shirish Gadgeel; Mary W. Redman; David R. Gandara; Karen Kelly;
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年(卷),期 -1(37),28
年度 -1
页码 -1
总页数 13
原文格式 PDF
正文语种
中图分类肿瘤学;
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专利

1. Phase II Trial of Cediranib in Combination With Cisplatin and Pemetrexed in Chemotherapy-Naive Patients With Unresectable Malignant Pleural Mesothelioma (SWOG S0905) [J] . Tsao Anne S., Miao Jieling, Wistuba Ignacio I., Journal of Clinical Oncology . 2019,第28期

机译：Cediranib的II期试验与顺铂和化疗 - 幼稚患者中的顺铂和聚氯乙烯联合，患有不可切除的恶性胸膜间皮瘤（Swog S0905）
2. Phase I Trial of Cediranib in Combination with Cisplatin and Pemetrexed in Chemonaive Patients with Unresectable Malignant Pleural Mesothelioma (SWOG S0905) [J] . Anne S. Tsao, James Moon, Ignacio I. Wistuba, Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer . 2017,第8期

机译：Cediranib的阶段I与顺铂相结合的Cisplatin和Pemetrexed在含有不可切除的恶性胸膜间皮瘤瘤（Swog S0905）
3. A Phase II Trial of First-Line Combination Chemotherapy With Cisplatin, Pemetrexed, and Nivolumab for Unresectable Malignant Pleural Mesothelioma: A Study Protocol [J] . Nobukazu Fujimoto, Keisuke Aoe, Toshiyuki Kozuki, Clinical lung cancer . 2018,第5期

机译：二铂，磷酸盐蛋白化疗的第一线组合化疗的II期试验，用于不可切除的恶性胸腔间皮瘤：研究方案
4. Feasibility trial assessing intrapleural photodynamic therapy combined with pleurectomy/decortication then chemotherapy in malignant pleural mesothelioma patients. [C] . Serge Mordon, Camille Munck, Ecaterina Surmei-Pintilie, International Photodynamic Association World Congress . 2019

机译：可行性试验评估腹膜内光动力学治疗与胸膜切除术/凝固患者患者在恶性胸膜间皮瘤患者中相结合。
5. Regulatory T cell blockade combined with pemetrexed in malignant pleural mesothelioma [D] . Anraku, Masaki. 2008

机译：调节性T细胞阻滞联合培美曲塞治疗恶性胸膜间皮瘤
6. Phase I Trial of Cediranib in combination with cisplatin and pemetrexed in chemo naive patients with unresectable malignant pleural mesothelioma (SWOG S0905) [O] . Anne S. Tsao, James Moon, Ignacio I. Wistuba, -1

机译：塞地尼布联合顺铂和培美曲塞的一期临床试验在未经化疗的恶性胸膜间皮瘤初治患者中的应用（SWOG S0905）
7. Phase II Trial of Cediranib in Combination With Cisplatin and Pemetrexed in Chemotherapy-Naïve Patients With Unresectable Malignant Pleural Mesothelioma (SWOG S0905) [O] . Anne S. Tsao, Jieling Miao, Ignacio I. Wistuba, 2019

机译：Cediranib的II期试验与顺铂和聚普拉特在化疗 - 天真患者中与不可切除的恶性胸膜间皮瘤患者（SWOG S0905）的组合

Phase II Trial of Cediranib in Combination With Cisplatin and Pemetrexed in Chemotherapy-Naïve Patients With Unresectable Malignant Pleural Mesothelioma (SWOG S0905)

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