Circulating microRNA 134 sheds light on the diagnosis of major depressive disorder

摘要

To identify a potential miRNA for diagnosing MDD, we firslty conducted literature review to find the target miRNAs. Then, we used a small set of samples to vaildate the target miRNAs. Finally, we used a large set of samples to independently validate the identified miRNA. Meanwhile, this miRNA was also validated in brain tissue of rat model.