Perspective on Intra-articular Injection Cell Therapy for Osteoarthritis Treatment

摘要

Construction of PEG/KGN micelles-covalently integrated HA hydrogels (HA/PEG/KGN). Synthetic route ( ) and schematic illustration ( ) of HA/PEG/KGN (KGN, kartogenin; PEG, polyethylene glycol; OH-PEG-NH , heterobifunctional amine-PEG-hydroxyl; DCC, dicyclohexylcarbodiimide; DMAP, dimethylaminopyridine; EDA, 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; SA, succinic anhydride; EDA, ethylenediamine).