T111. TOBACCO CIGARETTE SMOKING IS ASSOCIATED WITH REDUCTIONS IN FUNCTIONAL CONNECTIVITY ANATOMICAL CONNECTIVITY AND CORTICAL THICKNESS IN LARGE-SCALE NETWORKS

摘要

Abstinence from cigarette smoking is associated with disrupted interactions among the core cognitive resting state networks including the Salience (SN), Default mode (DMN) and Executive control (ECN). Unified multimodal methods [Resting state connectivity analysis, Diffusion Tensor Imaging (DTI) analysis, and cortical thickness analysis] were employed to test the hypothesis that the impact of cigarette smoking on the balance among these networks is due to alterations in white matter connectivity, functional connectivity and cortical thickness (CT) and that these metrics define fundamental differences between smokers and non-smokers.