20.2 CANNABINOID 1 RECEPTOR AVAILABILITY AND MEMORY FUNCTION IN FIRST EPISODE PSYCHOSIS: A MULTI-MODAL PET AND FUNCTIONAL MRI IMAGING STUDY

摘要

The neurobiology of memory deficits in psychosis remains poorly understood and unaddressed by current treatments. The cannabinoid 1 receptor (CB1R) modulates memory, and cannabinoids drugs can both induce psychotic symptoms and impair memory encoding. In view of this, we investigated memory and CB1R availability in first episode psychosis (FEP).