O10.2. EFFECTS OF ADJUVANT OMEGA-3 POLYUNSATURATED FATTY ACIDS ON WHITE MATTER IN INDIVIDUALS WITH RECENT-ONSET PSYCHOSIS TREATED CONCURRENTLY WITH RISPERIDONE

摘要

The use of omega-3 polyunsaturated fatty acids (PUFAs) as a potential therapeutic agent has generated considerable enthusiasm given their relative safety, minimal side effects, and low cost. Omega-3s have been demonstrated to play a role in the maintenance of myelin and mitigation of pro-inflammatory cascades. We examined the potential impact of adjuvant omega-3 PUFA treatment on white matter in early-phase psychosis patients treated with risperidone in the context of a double-blind placebo controlled randomized clinical trial.