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Gastric Xanthoma in the Pediatric Population: A Possible Herald for Malignancy?

机译:小儿胃黄瘤:恶性肿瘤的可能先兆?

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摘要

Gastric xanthoma is frequently an incidental finding on upper endoscopy in adults. Gastric xanthomas (GX) can be mistaken for malignancies and warrant prompt histologic diagnosis. The underlying etiology is not fully understood; however, it has been linked to gastritis and gastric cancer. GX in the pediatric population is largely unreported in the literature. Because of the relative rarity, documentation with case reports are essential to provide as much data as possible to see if there is a correlation between GX and malignant potential in the pediatric population. Our group is reporting two cases, a 10-year-old male and a 7-year-old male, both who presented with chronic dysphagia, upper abdominal pain, nausea, vomiting, and loss of appetite. Upper endoscopies for both patients revealed small polypoid lesions located in the antrum with foamy histiocytes on histology, leading to the diagnosis of gastric xanthoma.
机译:胃黄瘤通常是成年人上内镜检查的偶然发现。胃黄瘤(GX)可能被误认为是恶性肿瘤,应立即进行组织学诊断。病因尚不完全清楚。然而,它与胃炎和胃癌有关。儿科人群中的GX在文献中基本未报道。由于相对罕见,病例报告的文档对于提供尽可能多的数据以查看小儿人群中GX和恶性潜能之间是否存在相关性至关重要。我们的小组报告了两例,分别是10岁的男性和7岁的男性,均患有慢性吞咽困难,上腹痛,恶心,呕吐和食欲不振。两名患者的上层内窥镜检查显示在窦腔内有小息肉样病变,组织学上带有泡沫性组织细胞,可诊断为胃黄瘤。

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